After graduating from UALR as a Whitbeck Scholar, Mackie received her MA and PhD in Anthropology from The Ohio State University. Today, she is a professor of Biology at Ball State University. As a biological anthropologist and evolutionary biologist specializing in the biology of human and primate teeth, her research provides a unique lens for understanding biology at multiple scales—from individual life histories to population-level adaptations across evolutionary time, with teeth serving as extraordinary windows into human development and adaptation by recording physiological stress events through daily cellular movement markers that are never remodeled or erased.